Granuloma or not?

This is a 47 year old healthy male who had a chest radiograph for a chest injury.  A nodule was seen in the LUL, and a CT was done.  He does not smoke, nor had any exposure history.  The CT images are shown.  Does this require biopsy or is this a granuloma?  It was not present on a CXR 5 years ago.

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One Response to “Granuloma or not?”

  1. Gough Says:

    I think it’s probably a calcified granuloma. Calcifications are also present in the ipsilateral hilar node, and the spleen consistent with histoplasmosis. I would check histo serologies, place a PPD, and plan to do a follow-up CT scan in 3 months. If the nodule grows in the interim you could do a CT/PET or the nodule is probably amenable to CT guided needle biopsy.

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